The second major route of AH into the brain is through its production by a yeast called Candida albicans. Research over the last several decades has shown that alcoholics tend to rapidly convert alcohol to AH, but then convert AH to acetate very slowly, thus giving AH a chance to work its mischief in the body.1 And depending on a person's genetics, nutritional status, and exposure to other chemicals such as formaldehyde, which also utilize aldehyde dehydrogenase for their detoxification, even non-alcoholics may have difficulty rapidly detoxifying AH. However, the conversion of AH to acetate does not always occur quickly or smoothly and therein lies the problem. (Acetate is a form of acetic acid, the acid that makes vinegar sour.) Acetate can then serve as a fuel in cellular energy production. Then another enzyme "aldehyde dehydrogenase" must break the AH down into acetate. An enzyme called "alcohol dehydrogenase" converts alcohol into AH. The first step occurs primarily in the liver, although other organs such as the brain and kidney can also perform this stage of alcohol detoxification to a slight extent. However, this process takes time and occurs in several steps. Once in the body, alcohol is broken down into carbon dioxide and water. These beverages serve as carriers to get ethanol into the drinker's brain, promoting some degree of intoxication. These are alcohol consumption, Candida "the yeast syndrome," exhaust from cars and trucks, and cigarette smoking.Įthanol (more commonly known as alcohol) is the chemical contained in beer, wine, liquor and liqueurs that gets people drunk. There are four main routes that bring acetaldehyde (abbreviated here as "AH") into the human brain. It is a simple substance its chemical formula is CH3CHO yet acetaldehyde insidiously promotes damage to brain structure and function through numerous pathways. Acetaldehyde - A Common and Potent NeurotoxinĪcetaldehyde is hardly a household word in America, yet it is one of the most common neurotoxins in the lives of tens of millions of people.
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In other words, one loadout might be best suited for long-range combat and another will help you maximize your damage output in close quarters. Loadouts in this game are designed to allow you to relatively easily be able to swap between various attachments in order to make the most out of the current situation. Picking the best loadouts in Battlefield 2042 is kind of tricky. Even if it doesn’t quite boast the range of a gun like the DXR, its max range is still respectable enough to allow you to effectively operate at a distance in the majority of Battlefield 2042 scenarios. The SVK is perfect for taking down enemies in a few shots from nearly sniper rifle-level distances. If Marksman weapons are ultimately supposed to fall somewhere between snipers and assault rifles, then I tend to recommend the SVK over some of its close alternatives simply because its stopping power helps it fill that somewhat niche void. I think there is a solid argument to be made for the AK-24 over the M5A3, but the M5A3’s accuracy and reliability are hard to ignore. It’s not nearly as powerful as the NWT-50 so far as that goes, but it is more manageable, accurate, and generally reliable, which are all the sniper traits you’re looking for in the current meta. The DXR-1’s raw power means that you really only have to hit a shot or two with it to ruin someone’s day. That being said, the DXR-1 appears to be your best bet for a quality sniper rifle at the moment. They’re too slow, too inaccurate, and generally don’t fit into the PP-29 meta. Look, Battlefield 2042’s snipers are not in a great place at the moment. You’re definitely going to want to learn to love this for when the PP-29 is nerfed. While every other gun on this list suffers by virtue of not being the PP-29, it has to be said that LCMG is one of the best overall weapons that aren’t comically broken.Īctually, if it weren’t for the fact that the LCMG makes you painfully immobile, it might be able to stand up to the PP-29 by virtue of its massive magazine, low recoil, and pure stopping power. It’s one of the most hilariously broken weapons I can remember seeing in a competitive multiplayer game in quite some time, and I can’t believe it was allowed to exist in this state at launch. It absolutely shreds at close ranges, it can be equipped with absurdly large magazines, and it’s honestly pretty useful at longer ranges assuming that you find the right loadout for it. The PP-29 is fast, accurate, and powerful. The reason why it’s so hard to have a serious discussion about the best guns in Battlefield 2042 at the moment is that the PP-29 is so laughably overpowered that there’s really no reason to even bother to use anything else. So while it feels kind of silly to talk about Battlefield 2042‘s available arsenal when there is really only one option, here’s a brief look at a few of the best overall guns in the game and their ideal loadouts. The bad news is that there’s really only one gun in the game at the moment that is worth using, which is about as dull as you’d suspect it would be. The good news is that Battlefield 2042 eliminates much of the pain and confusion that come from needing to “choose” a gun by making one of the game’s weapons so absurdly powerful that there’s really no reason to use anything else. Well, so far as that goes, I’ve got some good and bad news for you. Battlefield 2042‘s launch hasn’t been… great, but anyone looking to try out the latest entry in this historic multiplayer franchise will probably want to go into the game with at least a little knowledge about which guns and weapons are currently dominating the meta. In working each issue through to completion we have been able to retain a beautiful lightness in our relationship that we both cherish. But we still keep working on it until we both say that we feel complete, we understand our own part and responsibility in the issue rather than simply blaming each other, are willing to go on, and there is an even deeper connection and sometimes even humor to the situation. Sometimes we can clear the issue in a matter of a few minutes, sometimes an hour and sometimes it can take several days. Most times we have been able to work things through on our own. The therapist was able to listen to both of us and help us come to a place of resolution that we both felt good about. In those three times we sought professional help because there was a blind spot for each of us. We used all the skill that we have and yet it was still unresolved. There have been three times in our relationship when we were unable to resolve an issue on our own. Most times we have been able We have been together for 40 years, married for 36. Antagonistic contention contention characterized by anger or enmity discord conflict quarrel: as, strife of the elements. Emulative contention or rivalry active struggle for superiority emulation. There have been three times in our relationship when we were unable to resolve an issue on our own. A striving or effort to do ones best earnest attempt or endeavor. We have been together for 40 years, married for 36. Activities should work all the major muscle groups of your body-legs, hips, back, chest, abdomen, shoulders, and arms. Physical activities to strengthen your muscles are recommended at least 2 days a week. Want more tips on how you can add a variety of activities to your life? Check this out. Learn more about additional types of physical activity that are right for you. You need to feel comfortable doing moderate-intensity activities before you move on to more vigorous ones. If you have a history of a chronic disease, consider telling your doctor you are planning to increase your physical activity, including moving to more vigorous activity. If you haven’t been very active lately, however, increase your physical activity level slowly. Some people like to do vigorous activity because it gives them about the same health benefits in half the time. A rule of thumb is that 1 minute of vigorous-intensity activity is about the same as 2 minutes of moderate-intensity activity. You can do moderate- or vigorous-intensity aerobic activity, or a mix of the two, each week. Learn more about getting started with physical activity to improve health. If you want to do more vigorous-level activities, slowly replace those that take moderate effort like brisk walking with more vigorous activities like jogging. If you are doing moderate-intensity physical activity, such as walking or hiking, you can talk, but not sing during the activity. Here are some examples of activities that require vigorous effort: If you’re being active at a vigorous level, you won’t be able to say more than a few words without pausing for a breath. You may use the Talk Test to gauge the intensity of your aerobic physical activity. Vigorous-intensity aerobic activity means you’re breathing hard and fast, and your heart rate has gone up quite a bit. Riding a bike on level ground or with few hills.Here are some examples of activities that require moderate effort: One way to tell if it’s a moderate-intensity aerobic activity is that you’ll be able to talk, but not sing the words to your favorite song. Moderate-intensity aerobic physical activity means you’re working hard enough to raise your heart rate and break a sweat. Intensity is how hard your body is working during a physical activity. As long as you’re doing aerobic physical activities at a moderate- or vigorous-intensity, they count toward meeting the aerobic guideline. From pushing a lawn mower, to taking a dance class, to walking or biking to the store – these types of activities and more count. Aerobic activity or “cardio” gets you breathing harder and your heart beating faster. The size of the pupil is controlled by muscles within the iris - one muscle constricts the pupil opening (makes it smaller), and another iris muscle dilates the pupil (makes it larger). Using the analogy of a camera, the pupil is the aperture of the eye and the iris is the diaphragm that controls the size of the aperture. Together, the iris and pupil control how much light enters the eye. This is due to the intense light from the flash being reflected by the red color of the retina. Depending on your direction of gaze when the photo is taken, your pupils might appear bright red. Someone takes your photo using the camera's flash function. There's another common situation when the pupil of the eye changes color - when When the cloudy lens is replaced by a clear intraocular lens (IOL) during cataract surgery, the normal black appearance of the pupil is restored. If the pupil has a cloudy or pale color, typically this is because the lens of the eye (which is located directly behind the pupil) has become opaque due to the formation of a cataract. The black color is because light that passes through the pupil is absorbed by the retina and is not reflected back (in normal lighting). Typically, the pupils appear perfectly round, equal in size and black in color. The function of the pupil is to allow light to enter the eye so it can be focused on the retina to begin the process of sight. The pupil is the opening in the center of the iris (the structure that gives our eyes their color). One of the most important parts of the eye isn't a structure at all - it's an open space. However, after asking about my options, he quickly dismissed the green beans because they are pre-marinated in butter beforehand and didn't really offer a veggie alternative except for fries (they do have a dedicated fryer). Knowing it was an appetizer portion (which was meant to be shared), I figured the shrimp would make a good entree with an additional side item such as a side salad or green beans. Not minding this change, I committed to it. He said the dish was still possible, but that I'd have to forgo the tequilla-lime butter it's traditionally prepared with in favor for just seasonings and oil. When the chef came out (I failed to catch his name) a short time later, I inquired as to the feasibility of the "drunken" shrimp because it seemed to be lighter than the others on such a hot day. I was intrigued by the more unique offerings such as the volcano nachos, taco salad, or "drunken" shrimp, all of which can be made gluten and dairy free, but shied away from the volcano nachos after seeing their enormous size as waiters carried them to fellow diner's tables. Dessert, too, is offered on the gluten-free menu, but it is not dairy free. Buffett fans should rest easy knowing they can get a gluten and dairy free Cheeseburger in Paradise. Like many chain restaurant's gluten free offerings, they have steak, seafood, and chicken in various different preparations such as sandwiches, entrees, and salads. I really appreciate that he took this step because it gave me confidence that I could make sure my meal was safe.Īfter perusing the menu, the revised offerings were greater in number, but at the same time nothing special. Once seated, I informed our waiter that I was both gluten and dairy free and he decided to send a chef out to talk to me so that I could ask about my options and rest assured that the order wouldn't get lost in translation. Upon my arrival I requested the gluten-free menu when checking in and found that they had them stacked next to the regular menus ready for any gluten-free diner coming through the door. I've read other Orlando blogger's experiences, such as Jen's from Celiac and Orlando, and knew that the restaurant's menu has been in flux for a while now but in doing research, found that the update menu has been fully implemented. Though the experience has faded in my mind, I remember that the menu was limited and that it took a couple tries to get a side salad without cheese and croutons. I've known about Margaritaville's gluten-free options for a while because I sampled from their gluten-free menu over a year ago. Admission does not require a park ticket, so it's a great option to spend a couple hours or a whole day. Minutes away from the two parks, CityWalk is a collection of shops, restaurants and movie theaters that provide a welcome retreat from hitting the parks and a welcome getaway for visitors and locals alike. Located in Universal's CityWalk complex, Magaritaville is a popular option for those seeking a gluten-free meal while on-property at Universal Orlando. Wanting to beat the heat and get away from it all, my dad and I decided it was time to pay Margaritaville a visit. What drew me to Jimmy Buffett's Margaritaville was Orlando's first week of truly hot weather and my curiosity about their recently revamped gluten-free menu. While his whole playlist doesn't apply, it's hard to resist his songs of summer on this Memorial Day Weekend as the city opens up to welcome summer in all her blazing glory. Though it may seem stereotypical, I do think at some level Jimmy Buffett's island tunes are the soundtrack of the Floridian lifestyle. As a born and bred Floridian, I take pride in my wacky state of residence and defend it against the countless jokes and obnoxious questions people have about the sunshine state (no, most of us don't go to Disney every day and yes, we do feel bad when the rest of the country is covered in snow). Perhaps the worst, but hardly the only, terrible example of this trend can be seen in the Congo war - flaring up again right now - in which over 90 percent of the several million dead were noncombatants. The number of noncombatant deaths jumped to as much as 50 percent of the 50 million-plus lives lost in World War II, and the sad toll has kept on rising ever since. In World War I, perhaps only 10 percent of the 10 million-plus who died were civilians. The pattern of the past century - one recurring in history - is that the deaths of noncombatants due to war has risen, steadily and very dramatically. The problem with the conclusions reached in these studies is their reliance on "battle death" statistics. In his Better Angels of Our Nature, Pinker goes a little further, noting that over the past 70-plus years the number of battle deaths per 100,000 people has fallen dramatically - with no spikes, just a couple of "blips." (In 2012, the total I see is back up to about 10.) In addition to this, the number of battle deaths per year, worldwide, has dropped since the end of World War II - with just a few spikes largely explained by the Korean War (1950-1953), Vietnam from the mid-‘60’s to mid-‘70s, and the strife in the Balkans and among former-Soviet republics in the ‘90s. First, the number of ongoing conflicts in a given year in which more than 1,000 people die in battle has declined, if a bit choppily, from 25 in the mid-80s to five in 2006. The Human Security Report bases its conclusion on some key trends. The Human Security Reportarrived at this conclusion, which former United Nations Secretary General Kofi Annan affirmed in its foreword as offering proof that "he world has become much less insecure over the past 20 years." At Harvard, psychology professor Steven Pinker has taken a very long view, finding that our era is far less brutal than ancient, medieval, or even early modern times. Yet a number of remarkably hopeful studies published recently suggest war is on the wane. Writing their Lessons of History in the tumultuous year 1968, Will and Ariel Durant observed that in "the last 3,421 years of recorded history, only 268 have seen no war." The 44 years since they made this observation have added not a single year of peace to that meager total. “Maniac” made it to track 11 in the setlist, nearing the end of the show. Gray also plays “The Story,” which is an unreleased track, and a cover of “Burnin’ Up” by the Jonas Brothers. Hits include songs like “The King” and “Generation Why” from his “Sunset Season” EP. In his first shows, he has played a set of 14 songs, including everything from big hits to unreleased tracks to covers. If fans want to see more of Gray, they can catch him in one of the 26 cities across North America. Though unlikely the intention, it hypes fans (or at least this fan) for his Comfort Crowd tour. This is the first fans have gotten to see of his noodle dancing in a while, as his most recent videos have only had short clips sparingly placed. In an interview with Billboard, Gray said his “favorite dance move is “wiggling … just like a little noodle!” Gray is a self-proclaimed “noodle dancer,” meaning he flops around like a noodle when he performs. In between all of this fighting, fans are treated to Gray lip-syncing and dancing on a stage with a microphone stand. They seem to be best friends rather than romantically involved, the only part that breaks from the “Scott Pilgrim vs. Dreamy vocals, dreamy production, dreamy man: Gray snaps both viewers and Barden back to reality with his lyrics, and by smashing a gumball machine over the dreamboat’s head.īarden and Gray make a dynamic pair throughout the music video, the two consistently looking out for each other. This scene plays over the bridge and the immediate chorus, the softest part of the song. He gets no written description, but it’s clear that this guy is Barden’s version of the heartbreaker from Gray’s lyrics. He’s the only one that Barden actually wants back, the only one she doesn’t want to fight against. Viewers are then shown the scariest ex of all: the dreamboat. The nice guy “just wants a hug” and “proposed last semester.” The art boy “writes poems about Jess” and “only listens to vinyl.” These two don’t fight. The nice guy and the art boy appear very quickly after each other. Viewers meet four exes: the meathead, the nice guy, the art boy and the dreamboat.Īs described by the text in the music video, the meathead “played QB in college, drinks too much beer, cries in the shower.” While Gray runs away from him, Barden takes him down with a steamer. Scott Pilgrim-style, she and Gray have to fight them off and survive until morning. In the video, from the alignment of the stars and the blood moon, Barden’s ex-boyfriends have risen up from the dead for one night of terror. The video for “Maniac” is a mini horror movie, playing into the release date near Halloween. He continues, “Now you’re manic, honestly, I’ve had it / listen to yourself, think you need to get some help.” Call them out Gray!Ī great song deserves a great music video, and Conan Gray delivered. Yes, this song is biased in Gray’s favor, but the guy wrote the song - cut him some slack. “Psychopathic, don’t be so dramatic / We had magic, but you made it tragic.” Here he comes to his senses, remembering that this partner is the problem, not Gray, who genuinely tried his best. However, in the bridge, Gray snaps back to reality, finally accepting that this relationship is doomed. “Now you’re breakin’ my heart / so, I show up at your place right away / Wipe the tears off of your face / while you beg me to stay.” Both of them are hypocrites, saying they hate the other while truly feeling anything but. It’s all bright sounds and fast beats, a complete opposite of what the lyrics might suggest.Ĭonan Gray continues his roast session of this mysterious heartbreaker, mocking them in the second verse while acknowledging how he gives into the temptation of helping the heartbreaker. It does not store any personal data.After the chorus, the song is carried by the production until the second verse. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The cookie is used to store the user consent for the cookies in the category "Performance". This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. The cookies is used to store the user consent for the cookies in the category "Necessary". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The cookie is used to store the user consent for the cookies in the category "Analytics". These cookies ensure basic functionalities and security features of the website, anonymously. Necessary cookies are absolutely essential for the website to function properly. In 1858, Vuitton debuted his lightweight, handcrafted canvas trunks, which were sturdy, rugged and equipped with convenient compartments. The most common trunks of the era were round, which weren’t ideal for toting and storing. Long before his brand would become known globally for its exemplary top-handle bags and stylish totes, Vuitton produced stackable and rectangular trunks. The craftsman opened a humble workshop on rue Neuve des Capucines and advertised his services with a small poster that read: “Securely packs the most fragile objects. In 1854, Vuitton launched his namesake company. He toiled as a box maker and packer for more than a decade and built relationships with royals and members of the upper class while working for the empress of France, Eugenie de Montijo. When he arrived in Paris, Vuitton made a living with his hands. With stops along the way to make money so that he could forge ahead, the journey took a couple of years, but reward was close at hand. The young Vuitton was 13 at the time and would need to travel on foot to get to the capital, which was hundreds of miles away. The company’s modest origins can be traced back to when its founder, Louis Vuitton (1821–92), wishing to free himself from the conventional lifestyle in his provincial French city of Anchay as well as a difficult stepmother, left in the early 1830s to make a new life in Paris. Priced at $4,200 USD €2800 euro’s or £2,400 GBP at Louis Vuitton store.The story behind iconic luxury brand Louis Vuitton - best known for its esteemed handbags, crossbody bags, leather goods, ready-to-wear clothing and more - is one of craft and innovation in the worlds of fashion, jewelry and furniture. Measuring 19.3′ x 17.3′ x 7.5′ (W x H x D), available colors black, galet, framboise, pink and brown. The shape is eye-catching and impressive, but it doesn’t scream for attention with an oversized LV logo, instead you will find the Louis Vuitton signature in small letters on the front. The most stunning is the new size, to give you an example – you can literally store your laptop inside. It’s an understated luxury, pure feminine, in delightful and soft colors like pink or beige. For the first time, it’s crafted in grained veau cachemire calfskin – in bigger size, softer and also light weighed. The second re-design is in 2014, the Louis Vuitton Lockit Bag has been restructured to match our time of fashion. A new leather tab with a padlock was embellished on the side, but the shape remains the same, new sizes were also introduced. The first re-design happened in 2006, the ‘lockit’ was reinvented and inspired by the distinctive closure system. And up until today, it’s still selling as a vintage piece. The original version was launched in 1958, it had an arched shape, a tote bag that looked quite modern in its time. You see, the Louis Vuitton Lockit Bag is not a ‘new’ invention, it has been redesigned, to be exact – for the second time. When it was about time to introduce the newest Lockit Bag to the Bag Obsessed, Louis Vuitton called up Michelle Williams to feature in their latest Fall Winter 2014 Ad Campaign.īut let us start at the beginning, let us give you some importance facts first before diving into the details. The success of their survival is predominantly based on a diverse diet. Places like Kruger National Park and Hluhluwe-Imfolozi are large strongholds of this magnificent antelope. Nyala have a population of roughly 32 000 and are most commonly found in game reserves and private farms throughout Southern Africa. The male develops long inward curved horns measuring roughly 65 cm in length. Males (bulls) are considerably larger than females (cows).īulls have an average weight of 115 kg, while cows have an average weight of 59 kg. Nyala are also one of the biggest spiral-horned antelopes found in Africa. These beautiful antelope have a slate-brown shaggy coat with white vertical stripes and spots on the flanks. The nyala antelope, scientifically named tragelaphus angasii, is a rather secretive species more easily seen at night. Northern and western bushbuck are more reddish with spots and stripes, while southern and eastern bushbuck are more yellow in colour with fewer markings. Interestingly, the colour of these antelope vary depending on the region in which they reside. The average weight of the bushbuck is 58 kg, making it the smallest of Africa’s spiral-horned antelope. It can be spotted in rainforests, wooded savanna, sub-desert, fynbos and montane forest. This is largely due to the antelope’s ability to forage, live and adapt to various climates. Inhabiting most of the African continent, their estimated population is over one million. Countries like Senegal and the southern half of Mauritania are also home to this unique species.īushbuck have a life expectancy of about 12 years in the wild. It is most commonly found in sub-Saharan Africa, particularly in South Africa, Zimbabwe, and Botswana. The bushbuck, scientifically known as tragelaphus scriptus, is a close relative to the nyala and kudu. To ensure you’re well versed on the different antelope types on your next African safari, here are several fun facts on the continent’s most revered horned animals. Making up Africa’s antelope with spiral horns are eight species. Meet the bushbuck, nyala, eland, lesser kudu, greater kudu, bongo, and sitatunga below to learn about their special quirks and characteristics. These ungulates are easily distinguishable from other African antelopes by their curly horns. Many people from around the world visit the mainland to travel on safari, in hopes of seeing these magnificent creatures in their natural habitat.Īmong the many types of antelope found in these regions, those with spiral horns are some of the most striking.Īfrican spiral-horned antelope fall under the ‘bushbuck tribe’, or Tragelaphini. Africa is home to more species of antelope than any other continent. |
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